Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8680645 | Alzheimer's & Dementia: Translational Research & Clinical Interventions | 2016 | 11 Pages |
Abstract
JNJ-54861911, a potent brain-penetrant BACE1 inhibitor, achieved high and stable Aβ reductions after single and multiple dosing in healthy participants.
Keywords
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Authors
Maarten Timmers, Bianca Van Broeck, Steven Ramael, John Slemmon, Katja De Waepenaert, Alberto Russu, Jennifer Bogert, Hans Stieltjes, Leslie M. Shaw, Sebastiaan Engelborghs, Dieder Moechars, Marc Mercken, Enchi Liu, Vikash Sinha, John Kemp,