Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8681346 | Brain Stimulation | 2018 | 13 Pages |
Abstract
The specific role for BDNF Val66Met in eyeblink conditioning, but not vestibulo-ocular reflex adaptation, saccade adaptation or visuomotor adaptation could be related to dominance of the role of simple spike suppression of cerebellar Purkinje cells with a high baseline firing frequency in eyeblink conditioning. Susceptibility of non-carriers to anodal tDCS in eyeblink conditioning might be explained by a relatively larger effect of tDCS-induced subthreshold depolarization in this group, which might increase the spontaneous firing frequency up to the level of that of the carriers.
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Authors
Rick van der Vliet, Zeb D. Jonker, Suzanne C. Louwen, Marco Heuvelman, Linda de Vreede, Gerard M. Ribbers, Chris I. De Zeeuw, Opher Donchin, Ruud W. Selles, Jos N. van der Geest, Maarten A. Frens,