Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8683685 | Epilepsy & Behavior | 2018 | 8 Pages |
Abstract
The cardiovascular system is under deep sympathetic influence in children with epilepsy. Although VNS seems to provide a substantial improvement by achieving increased parasympathetic effects in short-term therapy, the levels were still lower than those of healthy children after either short- or long-term therapy. Therefore, impaired cardiovascular autonomic regulation may be associated with the epileptic process itself as well as with the contribution of some additional factors. Overall, different aspects such as age, epilepsy duration, epileptic focus, seizure frequency, and AEDs should also be considered for their further possible effects on HRV during VNS therapy.
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Authors
Tugba Hirfanoglu, Ayse Serdaroglu, Ilker Cetin, Gokhan Kurt, Irem Y. Capraz, Filiz Ekici, Ebru Arhan, Erhan Bilir,