Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8683703 | Epilepsy & Behavior | 2018 | 11 Pages |
Abstract
Preclinical studies suggest that caffeine increases seizure susceptibility. In some cases, chronic use of caffeine may protect against seizures. Caffeine lowers the efficacy of several drugs, especially topiramate. It is unclear how these findings in models can be translated to the clinical condition. Until clinical studies suggest otherwise, caffeine intake should be considered as a factor in achieving and maintaining seizure control in epilepsy.
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Authors
Rick R. van Koert, Prisca R. Bauer, Ilse Schuitema, Josemir W. Sander, Gerhard H. Visser,