| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8684206 | Epilepsy Research | 2018 | 7 Pages |
Abstract
There is pronounced pharmacokinetic variability of VPA during pregnancy. Unbound concentrations are rarely requested. TDM should be used by measurements of both total and unbound concentrations since total concentrations may be misleading for efficacy and fetal exposure of VPA.
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Authors
Cecilie Johannessen Landmark, Anette Huuse Farmen, Margrete Larsen Burns, Arton Baftiu, Morten I. Lossius, Svein I. Johannessen, Torbjörn Tomson,