Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8684492 | European Journal of Paediatric Neurology | 2016 | 4 Pages |
Abstract
High-dose pramipexole therapy in BH4 deficiency can be complicated, like in Parkinson disease, by psychiatric adverse effects. Low-dose pramipexole therapy (â¼0.010Â mg/kg/day) has been safe and clinically effective on long-term follow-up, representing a helpful therapeutic option in patients with BH4 deficiency.
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Authors
Francesco Porta, Alberto Ponzone, Marco Spada,