Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8684545 | Experimental Neurology | 2018 | 12 Pages |
Abstract
UCB-derived MSC therapy preserved white matter brain structure following preterm HI, mediated by a suppression of microglial activation, promotion of macrophage migration and acceleration of self-repair within the preterm brain. UCB-derived MSC are neuroprotective, acting via peripheral and cerebral anti-inflammatory and immunomodulatory mechanisms.
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Authors
Jingang Li, Tamara Yawno, Amy E. Sutherland, Shanti Gurung, Madison Paton, Courtney McDonald, Abhilasha Tiwari, Yen Pham, Margie Castillo-Melendez, Graham Jenkin, Suzanne L. Miller,