A mimic peroxidase biosensor based on calcined layered double hydroxide for detection of H2O2

An enzymeless biosensor was explored from Cu–Mg–Al calcined layered double hydroxide (CLDH) modified electrode in this study. The Cu–Mg–Al CLDH greatly promotes the electron transfer between H2O2 and GCE, and it is exemplified toward the non-enzymatic sensing of H2O2. The results indicate that the Cu–Mg–Al CLDH exhibits excellent electrocatalytic property, high sensitivity, good reproducibility, long-term stability, and fast amperometric response toward reduction of H2O2, thus is promising for the future development of man-made mimics of enzyme in H2O2 sensors. This work opens a way to utilize simply Cu–Mg–Al CLDH as an electron mediator to fabricate an efficient H2O2 biosensor, which exhibits great potential applications in varieties of simple, robust, and easy-to-make analytical approaches in the future.