| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 868742 | Biosensors and Bioelectronics | 2009 | 4 Pages |
Abstract
Soluble molecularly imprinted nanoparticles were synthesised via iniferter initiated polymerisation and separated by size via gel permeation chromatography. Subsequent fractionation of these particles by affinity chromatography allowed the separation of high affinity fractions from the mixture of nanoparticles. Fractions selected this way possess affinity similar to that of natural antibodies (Kd 6.6 × 10−8) M and were also able to discriminate between related functional analogues of the template.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
António R. Guerreiro, Iva Chianella, Elena Piletska, Michael J. Whitcombe, Sergey A. Piletsky,