Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8687502 | NeuroImage: Clinical | 2018 | 24 Pages |
Abstract
We initially hypothesized that normal appearing WM myelin loss may determine the severity of early disease and the subsequent risk of clinically definite MS development. However, in contrast we found that WM lesion myelin loss was pivotal for MS conversion. Regional myelination measures may thus play an important role in future clinical risk stratification.
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Authors
Hagen H. Kitzler, Hannes Wahl, Judith C. Eisele, Matthias Kuhn, Henning Schmitz-Peiffer, Simone Kern, Brian K. Rutt, Sean C.L. Deoni, Tjalf Ziemssen, Jennifer Linn,