Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8687702 | NeuroImage: Clinical | 2018 | 11 Pages |
Abstract
To the best of our knowledge, this is the first study investigating changes in corpus callosum morphometry in normal ageing and AD by exploring both summarizing features (CCA, CIR and CCI) and the complete CC thickness profile in two independent cohorts using a completely automated algorithm. We showed that callosal circularity allows to discriminate between an important subgroup of the early AD spectrum (SCD) and age and sex matched healthy controls.
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Authors
Jeroen Van Schependom, Ellis Niemantsverdriet, Dirk Smeets, Sebastiaan Engelborghs,