Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8687843 | NeuroImage: Clinical | 2018 | 37 Pages |
Abstract
Our study provides evidence that impaired emotion processing in PD specifically affects male patients, and that hormones and genetics contribute to emotion recognition performance. Further research on the underlying neural, endocrinological and genetic mechanisms of specific symptoms in PD is of clinical relevance, as it can improve our understanding of the phenomenology and pathobiology of the disease and may allow a more personalized medicine.
Keywords
BDI-IIMoCAUPDRSCOMTEPICatechol-O-methyltransferaseNMSBAIMMSEVBMBOLDH&YLEDDmild cognitive impairmentMontreal Cognitive AssessmentFunctional magnetic resonance imaging (fMRI)MRIParkinson's diseaseParkinson's Disease (PD)echo planar imagingMagnetic resonance imagingfunctional magnetic resonance imagingfMRIGenderNon-motor symptomsGray matterMini-Mental State ExaminationUnified Parkinson's Disease Rating Scalevoxel-based morphometryMCIEmotionBeck Anxiety InventoryGeneticshealthy controls
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Authors
Julia Heller, Shahram Mirzazade, Sandro Romanzetti, Ute Habel, Birgit Derntl, Nils M. Freitag, Jörg B. Schulz, Imis Dogan, Kathrin Reetz,