Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8688506 | NeuroImage: Clinical | 2017 | 58 Pages |
Abstract
The susceptibility of the straight sinus in non-AI and AI patients was significantly lower than that in HCs (P < 0.001, P = 0.004, respectively, Bonferroni corrected), which may indicate an increased regional cerebral SvO2 in patients. The susceptibility of the straight sinus in non-AI patients positively correlated with ETPT (r = 0.573, P = 0.003, FDR corrected) while that in AI patients negatively correlated with the Rivermead Post Concussion Symptoms Questionnaire scores (r = â 0.582, P = 0.018, FDR corrected). The sensitivity, specificity and AUC values of susceptibility for the discrimination between mTBI patients and HCs were 88%, 69% and 0.84. In conclusion, the susceptibility of the straight sinus can be used as a biomarker to monitor the progress of mild TBI and to differentiate mTBI patients from healthy controls.
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Authors
Chao Chai, Rui Guo, Chao Zuo, Linlin Fan, Saifeng Liu, Tianyi Qian, E. Mark Haacke, Shuang Xia, Wen Shen,