| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8688623 | NeuroImage: Clinical | 2017 | 6 Pages |
Abstract
The increased diffusivity reflects the predicted microstructural tissue impairment in cSVD. Unexpectedly, an increased perfusion volume fraction was observed in patients. Future studies are needed to reveal the precise nature of the increased perfusion volume fraction. IVIM imaging showed that the increases of f and D in cSVD were both related to disease severity, which suggests the potential of IVIM imaging to provide a surrogate marker for the progression of cSVD.
Keywords
WMHCSVdPerfusion MR imagingbrain parenchymaIVIMMicrovasculaturePVSFOVNAWMSNRDGMROIFLAIRfluid attenuated inversion recoveryCerebral small vessel diseaseDiffusion weighted imagingdiffusion weightedbody mass indexBMIPerivascular spacesLacunar Strokewhite matter hyperintensityDeep grey matternormal appearing white matterregion of interestField of viewSignal-to-noise ratio
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Authors
Sau May Wong, C. Eleana Zhang, Frank C.G. van Bussel, Julie Staals, Cécile R.L.P.N. Jeukens, Paul A.M. Hofman, Robert J. van Oostenbrugge, Walter H. Backes, Jacobus F.A. Jansen,