Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8688696 | NeuroImage: Clinical | 2017 | 5 Pages |
Abstract
Administration of an acute does of anti-parkinsonian medication in PD does not affect free-water and FAt in key nigrostriatal structures. Free-water and FAt biomarkers reflect the chronic state of the nigrostriatal circuit, and therefore are potential viable biomarkers for disease-modifying therapeutic studies in PD.
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Authors
Jae Woo Chung, Roxana G. Burciu, Edward Ofori, Priyank Shukla, Michael S. Okun, Christopher W. Hess, David E. Vaillancourt,