| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8688978 | NeuroImage: Clinical | 2016 | 7 Pages |
Abstract
The present study further supports involvement of non-motor areas in ALS. Our results render homotopic rs-FC as assessed by NIRS a potential clinical marker for disease progression rate in ALS patients without executive dysfunction and a potential anatomical marker for ALS-specific degeneration of the CC and CSTs.
Keywords
DTIrs-FCALSFRS-rATLCorpus callosumTBSSFTDDPRNIRSCStTract based spatial statisticsResting-state functional connectivityInterhemispheric connectivityamyotrophic lateral sclerosisALSdiffusion tensor imagingfMRIfunctional magnetic resonance imagingcorticospinal tractNear-infrared spectroscopyfrontotemporal dementiaAnterior temporal lobewhite matterDisease durationfractional anisotropyHemoglobinPALSanterior commissurehealthy control
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Authors
Klaus Kopitzki, Andreas Oldag, Catherine M. Sweeney-Reed, Judith Machts, Maria Veit, Jörn Kaufmann, Hermann Hinrichs, Hans-Jochen Heinze, Katja Kollewe, Susanne Petri, Bahram Mohammadi, Reinhard Dengler, Andreas R. Kupsch, Stefan Vielhaber,