| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8692284 | Chinese Herbal Medicines | 2018 | 21 Pages |
Abstract
The LC-MS/MS method combinated with microdialysis is useful in the brain pharmacokinetic study of five protoberberine-type alkaloids. The results indicated that the rates of analytes absorption in insomnic rats were significantly higher than those in normal rats. Besides, the protoberberine-type alkaloids could bring a direct effect on the neuron in the hippocampus.
Keywords
Related Topics
Health Sciences
Medicine and Dentistry
Complementary and Alternative Medicine
Authors
Xiao-jun Zhang, Jia-hui Chen, Liang Luo, Wei He, Guang-hui Liu, Jing Gong, Yi-feng Zeng, Zhi-yong Xie, Qiong-feng Liao,