Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8693039 | Journal of Ginseng Research | 2018 | 9 Pages |
Abstract
Taken together, our findings suggest that PGE exerts antidepressant-like effect of CRS-induced depression by antineuroinflammatory and antioxidant (nuclear factor erythroid 2 related factor 2/heme oxygenase-1 activation) activities by inhibiting the hypothalamo-pituitary-adrenal axis mechanism. Further studies are needed to evaluate the potential of components of P. ginseng as an alternative treatment of depression, including clinical trial evaluation.
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Authors
Jong Hee Choi, Min Jung Lee, Minhee Jang, Hak-Jae Kim, Sanghyun Lee, Sang Won Lee, Young Ock Kim, Ik-Hyun Cho,