Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
869596 | Biosensors and Bioelectronics | 2009 | 5 Pages |
Abstract
We present the design, fabrication and optical investigation of photonic crystal (PhC) nanocavity drop filters for use as optical biosensors. The resonant cavity mode wavelength and Q -factor are studied as a function of the ambient refractive index and as a function of adsorbed proteins (bovine serum albumin) on the sensor surface. Experiments were performed by evanescent excitation of the cavity mode via a PhC waveguide. This in turn is coupled to a ridge waveguide that allows the introduction of a fluid flow cell on a chip. A response of ∂λ/∂c=(4.54±0.66)×105∂λ/∂c=(4.54±0.66)×105 nm/M is measured leading to a measured detection limit as good as Δm=4.0±0.6 fg or Δm/ΔA=(4.9±0.7)×102 pg/mm2in the sensitive area.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
D. Dorfner, T. Zabel, T. Hürlimann, N. Hauke, L. Frandsen, U. Rant, G. Abstreiter, J. Finley,