Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8696407 | Archives of Oral Biology | 2018 | 8 Pages |
Abstract
Tumor-derived supernatants may impair the function of tumor-infiltrating pDCs, which subsequently decreases the immune response of CD4+ T cells in human oral cancer through TGF-β- and IL-10- dependent mechanisms. Careful manipulation of these impaired pDCs may help develop an important alternative immunotherapy for the treatment of oral cancer.
Keywords
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Dentistry, Oral Surgery and Medicine
Authors
Nannan Han, Zun Zhang, Houyu Jv, Jingzhou Hu, Min Ruan, Chenping Zhang,