| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8696424 | Archives of Oral Biology | 2018 | 5 Pages |
Abstract
The effects of chronic smoking on oral mucosa led to the methylation of genes MRE11A PMS2, XRCC1 and MLH3, but resulted in a reduction of gene expression of MRE11A and PMS2, which showed â¥50% methylation. These results provide evidence that smoking cause methylation and reduced expression of repair genes.
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Authors
Celina Faig Lima Carta, Mônica Ghislaine Oliveira Alves, PatrÃcia Pimentel de Barros, Márcia Sampaio Campos, Jaqueline Scholz, Antonio Olavo Cardoso Jorge, Fábio Daumas Nunes, Janete Dias Almeida,