Article ID Journal Published Year Pages File Type
8696483 Archives of Oral Biology 2018 6 Pages PDF
Abstract
We identify that miR-186 serves as a tumor suppressor in OSCC. Downregulation of this microRNA may lead to a higher expression of oncogenic factor SHP2, which leads to activation of growth promoting signaling. Thus, miR-186 may be a novel and effective therapeutic agent for the treatment of OSCC.
Keywords
Related Topics
Health Sciences Medicine and Dentistry Dentistry, Oral Surgery and Medicine
Preview
MicroRNA-186 serves as a tumor suppressor in oral squamous cell carcinoma by negatively regulating the protein tyrosine phosphatase SHP2 expression
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