Article ID Journal Published Year Pages File Type
8696484 Archives of Oral Biology 2018 6 Pages PDF
Abstract
Together, in OC2 cells, magnolol induced [Ca2+]i rises by evoking partially PLC-dependent Ca2+ release from the endoplasmic reticulum and Ca2+ entry via PKC-sensitive store-operated Ca2+ entry. Magnolol also caused Ca2+-independent cell death. Therefore, magnolol-induced cytotoxicity may not be involved in activation mechanisms associated with intracellular Ca2+ mobilization in oral cancer cells.
Related Topics
Health Sciences Medicine and Dentistry Dentistry, Oral Surgery and Medicine
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