| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8696529 | Archives of Oral Biology | 2018 | 9 Pages |
Abstract
Antibacterial activity against S. mutans and the morphological description of damage induced by saliva and histatin 5 was demonstrated. Pyknotic nucleoids observed in S. mutans exposed to saliva, saliva plus histatin 5 and histatin 5 could be an apoptosis-like death mechanism. The knowledge of the damage generated by histatin 5 and its intracellular localization could favor the design of an ideal peptide as a therapeutic agent.
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Authors
A.M. Fernández-Presas, Y. Márquez Torres, R. GarcÃa González, A. Reyes Torres, I. Becker Fauser, H. RodrÃguez Barrera, B. RuÃz GarcÃa, R. Toloza Medina, J. Delgado DomÃnguez, J.L. Molinarà Soriano,