| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 869714 | Biosensors and Bioelectronics | 2006 | 6 Pages |
Abstract
To detect dioxin using a quartz crystal microbalance (QCM) immunosensor, anti-2,3,7,8-tetrachloro-p-dibenzodioxin (TCDD) monoclonal antibodies (MAbs) were produced as types of IgG1 and IgM, with mono 6-(2,3,6,7-tetrachloroxanthene-9-ylidene) hexyl succinate (as a hapten) conjugated with bovine serum albumin (dioxin-BSA). Furthermore, ScFv was generated from hybridoma-producing IgG1 MAb. Among these antibodies, ScFv showed excellent capability for dioxin detection using QCM immunosensors.
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Authors
Jong-Won Park, Shigeru Kurosawa, Hidenobu Aizawa, Hirokazu Hamano, Yoshitsugu Harada, Satoko Asano, Yutaka Mizushima, Megumu Higaki,