Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8699554 | Journal of Endodontics | 2018 | 8 Pages |
Abstract
Human tooth slices provide a valuable and easy-to-obtain model to investigate the effect of bioactive molecules used in dental pulp regeneration. This study showed for the first time that tooth slices could be kept viable under serum-free conditions for up to 3Â days. Iloprost promoted angiogenesis, increased new vessel formation, and induced collagen deposition. This study proposes the clinical value of iloprost as a drug for inducing angiogenesis that can increase the success of pulp regeneration.
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Authors
Sonntana DDS, Prasit DDS, PhD, Chalida N. DDS, PhD,