Incidence of multidrug resistance gene 1 3435C/T single nucleotide polymorphism in patients with amlodipine induced gingival enlargement - A case control study

Within the limits of the present study, it can be concluded that the susceptibility for drug-induced gingival overgrowth is not influenced by the MDR 1 C3435T single nucleotide polymorphism. Since the study was undertaken in a small sample size, definite conclusion cannot be drawn. Hence, further genetic studies in MDR 1 gene in a large population are necessary for justifying the genetic predisposition to drug-induced gingival overgrowth.