Article ID Journal Published Year Pages File Type
870126 Biosensors and Bioelectronics 2005 16 Pages PDF
Abstract

The current status of sensors capable of continuous measurement of analytes in biological media is reviewed. This review containing 173 references deals with devices whose use in single cells, tissue slices, animal models and humans has been demonstrated. In addition to sensors specific for glucose, lactate, glutamate, pyruvate, choline and acetylcholine, insights obtained from monitoring nitric oxide, Na+, K+, Ca2+, and dopamine are presented. Performance criteria for sensor performance are described as is the subject of biosensor calibration. Biocompatibility issues are dealt with in some detail as is the status of continuous blood glucose monitoring in humans.

Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
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