| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 870239 | Biosensors and Bioelectronics | 2007 | 6 Pages |
Abstract
In this study, we report a dose-dependent detection of odorant molecules in solution by rat olfactory receptor I7 (OR I7) in its membrane fraction. The OR I7 is immobilized on a gold electrode by multilayer bioengineering based on a mixed self-assembled monolayer and biotin/avidin system, which allows for a well-controlled immobilization of the bioreceptor within its lipid environment. The odorant detection is electronically performed in a quantitative manner by electrochemical impedance spectroscopy (EIS) measurements on samples and controls.
Keywords
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Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Yanxia Hou, Nicole Jaffrezic-Renault, Claude Martelet, Aidong Zhang, Jasmina Minic-Vidic, Tatiana Gorojankina, Marie-Annick Persuy, Edith Pajot-Augy, Roland Salesse, Vladimir Akimov, Lino Reggiani, Cecilia Pennetta, Eleonora Alfinito, Oscar Ruiz,