Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8707222 | Oral Oncology | 2018 | 8 Pages |
Abstract
Despite differences in clinical settings and anti-EGFR inhibitors used for treatment, response prediction by the Cluster3 signature and selected miRNAs was essentially the same. Translation into a useful clinical assay requires validation in a broader setting.
Keywords
ADCCEGFRHNSCCmAbECoGROCGEOAUCFFPEPFsMonoclonal antibodyantibody-dependent cellular cytotoxicityGene expression signaturesprogression-free survivalProgression free survivalSecond line treatmentWorld Health OrganizationHead and neck cancereastern cooperative oncology groupAnti-EGFRconfidence intervalformalin-fixed paraffin-embeddedMiRNAhazard ratioGene Expression OmnibusWHOreceiver operating characteristicEpidermal growth factor receptor
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Authors
Marco Siano, Vittoria Espeli, Nicolas Mach, Paolo Bossi, Lisa Licitra, Michele Ghielmini, Milo Frattini, Silvana Canevari, Loris De Cecco,