Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8707261 | Oral Oncology | 2018 | 10 Pages |
Abstract
Despite showing a similar mutational profile, our comparative genomic analysis revealed distinctive features in OSCC and L/P-SCC. Some of these genes and cellular processes are likely to affect the cellular response to radiation or cisplatin. Genomic characterizations may guide or enable personalized treatment in the future.
Keywords
HRDOSCCCrtLSThomologous recombination deficiencyCNAsSPMSTCGAThe cancer genome atlasDNA sequence analysisGeneral surgerymutationOral cancerChemoradiotherapyLaryngeal neoplasmsPharyngeal neoplasmsHomologous recombinationHuman papillomavirusHPVGenomicsoral squamous cell carcinomaHead and neck squamous cell carcinomaFanconi anemiaCopy number aberrations
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Authors
David M. Vossen, Caroline V.M. Verhagen, Marcel Verheij, Lodewyk F.A. Wessels, Conchita Vens, Michiel W.M. van den Brekel,