| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8709063 | Sleep Medicine | 2018 | 15 Pages |
Abstract
Compared to normal individuals, patients exhibited an impairment of the LTD-like mechanisms induced by inhibitory rTMS, thus adding support to the involvement of GABA in RLS pathophysiology. Although future studies with a larger population are needed, TMS is confirmed to be effective in noninvasive probing of the neurophysiology and neurochemistry of RLS.
Keywords
NaArTMSTMSPLMSRLSRMTACCN-Acetyl-AspartateFirst Dorsal InterosseousSleep disordersresting motor thresholdlong-term depressionElectroencephalographyEMGelectromyographyRepetitive transcranial magnetic stimulationTranscranial magnetic stimulationPaired associative stimulationlong-term potentiationLTPFDIrestless legs syndromeprimary motor cortexanterior cingulate cortexLTDnot significantMotor evoked potentialsMEPsPASEEGNeuromodulationPSGPolysomnographyGABAgamma-amino-butyric acid
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Authors
Giuseppe Lanza, Bartolo Lanuzza, Debora Aricò, Mariagiovanna Cantone, Filomena Irene Ilaria Cosentino, Rita Bella, Giovanni Pennisi, Raffaele Ferri, Manuela Pennisi,