Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8711484 | Annales de Dermatologie et de Vénéréologie | 2017 | 7 Pages |
Abstract
Detailed clinical examination is recommended in children presenting GCT to screen for multiple forms and for signs of malformation suggestive of a genetic syndrome. Ours is the first case to be described of Noonan syndrome complicated by JMML associated with multiple GCT. This association once again raises the important question of the role of the Ras-MAPK signalling pathway in the development of benign and malignant tumours of solid organs or blood, associated with genetic syndromes.
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Authors
J. Castagna, J. Clerc, A.-S. Dupond, C. Laresche,