| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8713002 | Journal of Allergy and Clinical Immunology | 2018 | 18 Pages |
Abstract
Therapeutic intervention of Notch signaling by SAHM1 inhibits allergic airway inflammation in mice and is therefore an interesting new topical treatment opportunity in asthmatic patients.
Keywords
GSIRetinoic acid–related orphan receptor γtMAMLRBPJTH2 immunityIL-4RRORγtMLNStat6GATA3HDMNICDFOXP3BHRBALDMSOAllergic asthmaBronchial hyperreactivityforkhead box P3Notch intracellular domainMastermind-likeDimethyl sulfoxideDendritic cellTranscription factorbronchoalveolar lavageSignal transducer and activator of transcription 6Pulmonary resistanceγ-secretase inhibitorNotch signalingHouse dust miteMediastinal lymph nodeIL-4 receptor
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Authors
Alex PhD, Irma MSc, Jeffrey E. BSc, Melanie BSc, Marjolein J.W. BSc, Menno BSc, Ingrid BSc, Raymond E. PhD, Henk C. MD, PhD, Louis PhD, Derk PhD, R.W. PhD,