| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8713184 | Journal of Allergy and Clinical Immunology | 2018 | 12 Pages |
Abstract
Two years of allergen immunotherapy were effective but insufficient for long-term tolerance. Allergen-specific TH2 cells most closely paralleled the transient clinical outcome, and it is likely that recurrence of the T-cell drivers of allergic immunity abrogated the potential for durable tolerance. On the other hand, the persistence of IgE blocking antibody 1Â year after discontinuation might be an early indicator of a protolerogenic mechanism.
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Authors
Amedee PhD, Mohamed H. PhD, Kristina M. PhD, Tielin PhD, Erik PhD, Guy W. MD, Peter A. PhD, Stephen J. PhD, Alkis MD, Gerald T. MD, PhD, William W. PhD, Stephen R. MD,