Inflammatory mediators mediate airway smooth muscle contraction through a G protein-coupled receptor-transmembrane protein 16A-voltage-dependent Ca2+ channel axis and contribute to bronchial hyperresponsiveness in asthma

Article ID	Journal	Published Year	Pages	File Type
8713273	Journal of Allergy and Clinical Immunology	2018	60 Pages	PDF

Keywords

5-HT CLCA GCaMP3 TMEM16A VDCC ASMC MLCK LTD4 TxA2 RRS MCH IP3R PLC IP3 GPCR SMC OVA CTR ASM Inositol 1,4,5-triphosphate Asthma Ovalbumin Thromboxane A2 Hypersensitivity Sarcoplasmic reticulum myosin light chain kinase Smooth muscle cell Airway smooth muscle cell genetically encoded calcium indicator Airway smooth muscle Soci phospholipase C Leukotriene D4 Methacholine not significant knockout Fluorescence ratio Inflammatory mediator Voltage-dependent Ca2+ channel Control IP3 receptor G protein-coupled receptor

Related Topics

Life Sciences Immunology and Microbiology Immunology

Preview

Inflammatory mediators mediate airway smooth muscle contraction through a G protein-coupled receptor-transmembrane protein 16A-voltage-dependent Ca2+ channel axis and contribute to bronchial hyperresponsiveness in asthma

Authors

Pei PhD, Wei PhD, Jie BS, Tao BS, Xin PhD, Yan-Yan MS, Cheng-Hai PhD, Zhong MS, Yun-Qian PhD, Fan BS, Ye-Qiong BE, Li-Sha BS, Ping PhD, Cai-Ping PhD, Ji MMed, Da-Quan MMed, Liang MD, Xiao-Hao PhD, Min-Sheng PhD,