| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8713274 | Journal of Allergy and Clinical Immunology | 2018 | 39 Pages |
Abstract
This study identifies an autoimmune endotype of severe asthma that can be identified by the presence of sputum autoantibodies against EPX and autologous cellular components.
Keywords
MEABCA-1EPXB cell–activating factor of the TNF familyTCCOCsCRSautoantibodiesdsDNAdouble-stranded DNAEosinophilic asthmaSevere asthmaanti-nuclear antibodyanti-nuclear antibodieseosinophil peroxidaseEosinophiliaANABAFFImmunoprecipitationstandard error of estimateSputumautoimmunityEETSEEChronic rhinosinusitisLDHLactose dehydrogenasefeGhealthy controloral corticosteroid
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Authors
Manali PhD, David C. PhD, Katherine MSc, Melanie RRT, Chynna Margaret RRT, Elizabeth A. PhD, Sergei I. PhD, Ana BSc, Hanah BSc, James PhD, James J. PhD, Paige PhD, Parameswaran K. MD, PhD, FRCP, FRCPC,