T-cell receptor Î±Î²+ and CD19+ cell-depleted haploidentical and mismatched hematopoietic stem cell transplantation in primary immune deficiency

Article ID	Journal	Published Year	Pages	File Type
8713291	Journal of Allergy and Clinical Immunology	2018	38 Pages	PDF

Abstract

CD3+TCRÎ±Î²+ and CD19+ cell-depleted haploidentical or mMUD HSCT is a practical and viable alternative for children with a range of PIDs.

Keywords

SCID anti-thymocyte globulin GvHD HSCT HHV-6 TPN mismatched unrelated donor aGVHD ATG EFs TCr TMA PID CTL natural killer Event-free survival Acute graft-versus-host disease Graft-versus-host disease cytomegalovirus CMV cytotoxic T lymphocyte Haploidentical thrombotic microangiopathy Human herpesvirus 6 Hematopoietic stem cell transplantation Total parenteral nutrition primary immunodeficiency severe combined immunodeficiency T-cell receptor

Related Topics

Life Sciences Immunology and Microbiology Immunology

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T-cell receptor Î±Î²+ and CD19+ cell-depleted haploidentical and mismatched hematopoietic stem cell transplantation in primary immune deficiency

Authors

Ravi M. MD, DRCPSC, Reem MD, Zohreh PhD, Waseem MD, PhD, Persis PhD, FRCP, FRCPath, Robert MD, Kanchan MRCPCH, Giovanna MD, Juliana M.F. MD, Austen MD, PhD, Dawn PhD, David DipSc, MSc, Jane MD, Andrew J. MD, Roderick PhD, DCH, FRCPCH, Intan Juliana MD,