Pluripotent stem cell models of Blau syndrome reveal an IFN-Î³-dependent inflammatory response in macrophages

Article ID	Journal	Published Year	Pages	File Type
8713821	Journal of Allergy and Clinical Immunology	2018	22 Pages	PDF

Keywords

SCF Nucleotide-binding oligomerization domain 2 RUV MDP NOD2 M-CSF muramyl dipeptide TPO NF-κB GSEA IPSC qPCR DAPI RNA-seq IFN-γ gRNA 4′-6-diamidino-2-phenylindole dihydrochloride Quantitative PCR chromatin immunoprecipitation Gene Set Enrichment Analysis RNA sequencing Thyroperoxidase guide RNA Induced pluripotent stem cell Blau syndrome Stem Cell Factor nuclear factor κB macrophage colony-stimulating factor monocyte-derived macrophages CHiP

Related Topics

Life Sciences Immunology and Microbiology Immunology

Preview

Pluripotent stem cell models of Blau syndrome reveal an IFN-Î³-dependent inflammatory response in macrophages

Authors

Sanami MD, Naotomo MD, PhD, Yuri PhD, Akira MD, PhD, Fumiko PhD, Kazuki BSc, Mitsujiro PhD, Ayako MSc, Katsunori MSc, Akitsu PhD, Isao PhD, Yasuhiro MD, PhD, Ryuta MD, PhD, Toshio MD, PhD, Hiroyuki MD, PhD, Tatsutoshi MD, PhD, Megumu K. MD, PhD,