Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8713929 | Journal of Allergy and Clinical Immunology | 2017 | 35 Pages |
Abstract
This study confirms the previous reports that thymus transplantation can reconstitute T cells in patients with cDGS but with frequent autoimmune complications in survivors.
Keywords
CTLA4cortical thymic epithelial cellcTECThymus transplantationDGsmTECLCLEpCAMcDGSHSCTTregSCIDFOXP3TCrATGTECTRECcytotoxic T lymphocyte–associated antigen 4antithymocyte globulinautoimmune regulatorforkhead box P3Lymphoblastoid cell linethymic epithelial cellmedullary thymic epithelial cellDiGeorge SyndromecytomegalovirusCMVcytokeratinchargeRegulatory T epithelial cell adhesion moleculeAIREHematopoietic stem cell transplantationsevere combined immunodeficiencyT-cell receptor
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
Authors
E. Graham FRCPCH, Melissa BSc, Kimberly PhD, Jesmeen MRCPCH, Joe FRCS, Anna PhD, Neil FRCPATH, Neil MB, BSc, Konstantinos PhD, Stuart PhD, Jolanta MD, Ronald FRCPCH, Michael FRCPATH, Blythe PhD, Hans Christian MD, H. Bobby PhD, Lizzie RCN, Winnie PhD,