Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8714197 | The Journal of Allergy and Clinical Immunology: In Practice | 2018 | 11 Pages |
Abstract
Severe asthma is associated with significant morbidity and is a highly heterogeneous disorder. Severe asthma in adolescence has some unique elements compared with the features of severe asthma a medical provider would see in younger children or adults. A specific focus on psychological issues and adherence highlights some of the challenges in the management of asthma in adolescents. Treatment of adolescents with severe asthma now includes 3 approved biologic phenotype-directed therapies. Therapies available to adults may be beneficial to adolescents with severe asthma. Research into predictors of specific treatment response by phenotypes is ongoing. Optimal treatment strategies are not yet defined and warrant further investigation.
Keywords
GERDFDAATSERSACTFVCLTRAICSLAMADifficult-to-treat asthmaSevere asthmaLeukotriene receptor antagonistEuropean Respiratory SocietyAmerican Thoracic Societygastroesophageal reflux diseaseBiologicsAdherenceBronchial thermoplastyAsthma control testPsychosocialFood and Drug AdministrationLABAGlobal Initiative for Asthmaforced vital capacityPhenotypeAdolescentInhaled corticosteroidGINA
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Authors
Gregory T. MD, Ronina MD, Alyssa A. MD, Theresa W. MD,