| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8715642 | Journal of Dermatological Science | 2018 | 10 Pages |
Abstract
Periostin contributes to fibrosis by enhancing TGF-β signaling via Smad 7 inhibition, which may lead to ECM deposition and periostin generation.
Keywords
DAPIR-SMADTGF-βI-SmadRPNdiffuse cutaneous SSclimited cutaneous SSclcSScdcSScNHDFsEGR-1ECMIPFSSCα-SMAMMPPBSDMEMFBSGAPDH4,6-diamidino-2-phenylindolesystemic sclerosistransforming growth factor-βfetal bovine serumnormal human dermal fibroblastsidiopathic pulmonary fibrosisFibrosisExtracellular matrixmatrix metalloproteinasePhosphate-buffered salineDulbecco’s modified eagle’s mediumearly growth response-1Smad proteinsPeriostinglyceraldehyde-3-phosphate dehydrogenase
Related Topics
Health Sciences
Medicine and Dentistry
Dermatology
Authors
Miwa Kanaoka, Yukie Yamaguchi, Noriko Komitsu, Carol A. Feghali-Bostwick, Masahiro Ogawa, Kazuhiko Arima, Kenji Izuhara, Michiko Aihara,