Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8715659 | Journal of Dermatological Science | 2018 | 8 Pages |
Abstract
Our data indicated that PAK1 is upregulated in CTCL. PAK1 silencing induced apoptosis and inhibited cell growth by stimulating the expression of PUMA and p21. Thus, PAK1 may be a potential tumor marker and therapeutic target of CTCL.
Keywords
PBS7-amino-actinomycin-Dtris buffered saline with tween-207-AADCTCLPAK1P21TBSTDEGsqRT-PCRPBMCDMSOIHCImmunohistochemistryKEGG یا Kyoto Encyclopedia of Genes and Genomes Kyoto Encyclopedia of Genes and GenomesDimethylsulfoxidePeripheral blood mononuclear cellSézary syndromephosphate buffer salineMycosis fungoidesCutaneous T cell lymphomaquantitative real-time polymerase chain reactionPUMABIDDifferentially expressed genes
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Authors
Yimeng Wang, Xiaoguang Gu, Weiwei Li, Qian Zhang, Chunlei Zhang,