| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8715677 | Journal of Dermatological Science | 2018 | 9 Pages |
Abstract
This is the first report to prove that the Sendai vector system facilitates the reliable reprogramming of patient keratinocytes into transgene-free iPSCs, providing another pluripotent platform for personalized diagnostic and therapeutic approaches to RDEB.
Keywords
DAPINHEKMitomycin CRDEBSendai virus vectorSVVOct4IPSCPBSRT-PCRbFGFMEFMMC4′,6-diamidino-2-phenylindoleCRISPR/Cas9MOIInduced pluripotent stem cellbasic fibroblast growth factoroctamer-binding transcription factor 4Phosphate-buffered salinemouse embryonic fibroblastsreverse transcription polymerase chain reactionmultiplicity of infectionKeratinocyteNormal human epidermal keratinocyterecessive dystrophic epidermolysis bullosaepidermolysis bullosa
Related Topics
Health Sciences
Medicine and Dentistry
Dermatology
Authors
Wakana Matsumura, Yasuyuki Fujita, Chihiro Nakayama, Satoru Shinkuma, Shotaro Suzuki, Toshifumi Nomura, Riichiro Abe, Hiroshi Shimizu,