| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8716201 | Journal of Investigative Dermatology | 2018 | 4 Pages |
Abstract
Cancer cells are highly plastic and adopt multiple phenotypic states that contribute to tumor progression. Heppt et al. demonstrate that the homeodomain transcription factor Msh homeobox 1 reprograms melanoma cells to a precursor state associated with melanoma progression and increased liver metastasis. Identification of this new role for Msh homeobox 1 may facilitate the development of new therapies that limit melanoma dissemination.
Related Topics
Health Sciences
Medicine and Dentistry
Dermatology
Authors
Fernanda Faião-Flores, Keiran S.M. Smalley,