| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8716469 | Journal of Investigative Dermatology Symposium Proceedings | 2018 | 7 Pages |
Abstract
Alopecia areata (AA) is an autoimmune disorder characterized by T lymphocytic infiltrates around the bulbar region of hair follicles. Statins have surfaced as potential therapeutic agents for AA, partly because of their modulation of the JAK/STAT pathway. Some data indicate that statins are a possible option for acute, but not chronic, longstanding AA. Animal studies suggest that treatment with statins increases CD4+/CD25+/Foxp3+ populations in AA-affected mice.
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Authors
Jessica Cervantes, Joaquin J. Jimenez, Gina M. DelCanto, Antonella Tosti,