| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8716565 | Journal de Mycologie Médicale / Journal of Medical Mycology | 2018 | 6 Pages |
Abstract
Results revealed that histatin-5 is able to revert MDR phenotype and may be considered a potential alternative MDR inhibitor. Since Pdr5p is homologous to Candida albicans CaCdr1p and CaCdr2p, data obtained might be extrapolated to these transporters, inferring that associating fluconazole and histatin-5 may be a useful tool to circumvent failure treatments of infections caused by Candida MDR strains.
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Authors
J.A. da Rocha Curvelo, L.F. Reis de Sá, D.C. Moraes, R.M. Soares, A. Ferreira-Pereira,