| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8721205 | Clinical Immunology | 2018 | 27 Pages |
Abstract
Profound defects in Th17 cells and Tregs were observed in all patients with impaired STAT3 phosphorylation, indicating that DOCK8 plays a pivotal role in the STAT3 signaling pathway. These findings together with decrease in memory B cells and defective DOCK8 expression by flow cytometry can confirm the diagnosis.
Keywords
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Authors
Safa S. Meshaal, Rabab E. El Hawary, Alia Eldash, Bodo Grimbacher, Nadezhda Camacho-Ordonez, Dalia S. Abd Elaziz, Nermeen M. Galal, Jeannette A. Boutros, Shereen M. Shawky, Aisha M. Elmarsafy,