Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8721424 | Clinical Immunology | 2018 | 20 Pages |
Abstract
We review the importance of small non-coding microRNAs for the generation of germinal center B cells and their differentiation in antibody-secreting plasma cells. In the last part, we briefly elucidate the role of microRNAs in some plasma cell disorders.
Keywords
BLIMP-1S1PACPADGCR8DiGeorge syndrome critical region 8BCL6MITFPlasmablastiNKTdouble strand DNAActivation-induced cytidine deaminaseIRF4BACH2SMMMGUSBCL2-like 11PAX5TNFautophagy proteinMRL-lprXBP1SHMCSRdsDNAATGBCRASCMcl-1ERKc-MybRheumatoid arthritisantibody secreting cellanti-citrullinated protein antibodiesAktsomatic hypermutationimmunoglobulin interleukinclass switch recombinationBAFFinvariant natural killer T cellplasma cellInterferon regulatory factor 4Microphthalmia-associated transcription factortumor necrosis factorphosphatase and tensin homologMyeloid cell leukemia 1Systemic lupus erythematosusSLEBIMGerminal centerMultiple myelomaSmoldering myelomaMiRNAX-box binding protein 1PtenSHIP-1AIDextracellular signal-regulated kinasemonoclonal gammopathy of undetermined significanceB cell receptor
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Authors
Julia Meinzinger, Hans-Martin Jäck, Katharina Pracht,