Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8721609 | Diabetes & Metabolism | 2018 | 5 Pages |
Abstract
Women with GDM have significantly lower circulating neuregulin 4 levels compared with healthy pregnant controls, and the AUCGlucose is negatively and independently associated with neuregulin 4 during pregnancy. Neuregulin 4 is positively correlated with irisin during pregnancy, as well as in a longitudinal fashion. Future studies are now needed to better elucidate the precise pathomechanisms of the regulation of BAT-secreted adipokines during pregnancy.
Keywords
ANGPTL8FGF21AFABPHDLFFAGDMHOMA-IRBATOGTThigh-density lipoproteinAdipokineOral glucose tolerance testFree fatty acidsAmerican Diabetes AssociationFasting insulinPregnancybrown adipose tissuetriglycerideEnzyme-linked immunosorbent assayELISAGestational diabetes mellitusbody mass indexBMIfibroblast growth factor 21Low-density lipoproteinLDLInsulin resistanceADAAngiopoietin-like protein 8Adipocyte fatty acid-binding protein
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Authors
S. Kralisch, A. Hoffmann, J. Kratzsch, M. Blüher, M. Stumvoll, M. Fasshauer, T. Ebert,